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As sensitivity analysis to account for the bounded and ordinal nature of the mDISCERN, GQS, and JAMA scores, ordinal logistic regression was additionally performed, with each engagement metric entered individually as in the linear models above

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Ask about red-flag symptoms that require immediate medical attention: Chest pain or syncope (fainting) Severe, persistent abdominal pain (possible pancreatitis) Persistent vomiting or signs of dehydration Acute vision changes (potential retinopathy with rapid glucose improvement) New or worsening psychiatric symptoms Ask specific questions , such as: What is the optimal timing for taking these medications